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KMID : 0378019640070070079
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New Medical Journal
1964 Volume.7 No. 7 p.79 ~ p.84
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Effects of Ginseng upon Tolerance of Mice to Positive Radial Acceleration(Ⅱ)
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Abstract
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The influence on tolerance of mice positive radial acceleration has been previously reported (j). The present paper described the change on tolerance of mice exposed Ao positive radial acceleration after injected with Ginseng ethanol extract.
A total 1,540 of normal male and female mice were injected with Ginseng ethanol extract (2 mg/kg/day)´ for 4 days. They were then exposed to 2.4, 3, 5, 7, 13, 17, 23 and 29 positive radial acceleration. Percent mortality of the both groups, normal group reported previously (1) and Ginseng group, were compared.
The conclusion abtained from the results is as follow.
(1) Significant effects on increasing tolerance to each positive radial acceleration could be recognized in mice to which Ginseng ethanol extract (2 mg/kg/day)_was injected for 4 days.
(2) A formula was obtained to express the relationships between g-force, exposure time and percentage of response, which may be presented as follows.
_ (p´50)z
P=1~ 10 P´ e 200 dp,
2,z ,-
i 1 1
j 0 1 ( 0.00000000003171 1 is 106606.79 1 15 ( 0.00000000003171 1 1. l
P´=1001 t ` 1 J t t I ` I J
g1.5 g2.993 g1.5
i _ (g1.5)t1.50.00000000003171
I p 0.01493 t1.5+1066.0679
Where;
I P; predicted percentage of mortality of mice exposed to positive radial acceleration after injected with Ginseng extract.
p´; modified probacent
p; probacent of mortality g; g-force.
t; duration under the exposure to g-stress.
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